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Abstract

This research was conducted because of the widespread assumption in many Asian nations that consuming unripe Carica papaya L fruit during the first months of pregnancy may result in miscarriage. The objective of the current research was to evaluate the impact of administering hydroethanolic extract of unripe fruit of Carica papaya L (EECP). Materials and Methods: We took pregnant female rats and put them into four groups: Group I (control), Group II (200mg/kg p.o. EECP), Group III (400mg/kg p.o. EECP), and Group IV (Ethinyl estradiol 0.02mg/kg.p.o). After the extract was given by mouth, a laparotomy was done and the uteri were looked at to see how many implantation sites there were. At the conclusion of the trial, all rats in each group were euthanized. We found out what the blood and chemical levels were. The modification of hormone levels was also examined. The current investigation indicated that there are substantial discrepancies in the biochemical parameters. The hormonal stability had also changed, which led to the end of the pregnancy. The research demonstrated that hydroethanolic extract impeded the implantation process. The lack of implantation may be attributed to antizygotic and blastocytotoxic properties of the extract.

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Section
Review